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Filtered Search Results
ABclonal Technology Nanog Rabbit mAb
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The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation renewal and pluripotency The encoded protein can block ES cell differentiation and can also autorepress its own expression in differentiating cells Several transcript variants encoding different isoforms have been found for this gene
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Cayman Chemical sPLA2TYP IB RabbIt Moncl 100uL
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A natural non-caloric sweetener and an active metabolite of rebaudioside A inhibits the proliferation of MDA-MB-231 cells at 250 Ug/ml active against M. tuberculosis (MIC 3.75 Ug/ml)
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ABclonal Technology HSF1 Rabbit mAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE) This protein plays a role in the regulation of lifespan Expression of this gene is repressed by phosphorylation which promotes binding by heat shock protein 90
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Cayman Chemical p70S6KNTerm RabbIt Moncl 100uL
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A flavonoid inhibits Cav3 2 and high-voltage-activated calcium currents in whole-cell patch-clamp assays using HEK293 cells (IC50s 0 912 and 4 765 UM respectively) reduces the activity of ALR2 (IC50 6 2 UM for the recombinant human enzyme) inhibits proliferation of PC3 and DU145 prostate cancer cells (IC50s 18 4 and 29 1 UM respectively) reduces mechanical allodynia in a mouse model of neuropathic pain induced by partial sciatic nerve ligation at 20 and 30 mg/kg
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Biotium Secondary Antibody Mouse IgG Rabbit CF583R 1/EA
This product is prepared by labeling highly cross-adsorbed rabbit anti-mouse IgG (H plus L) with CF and reg 583R dye CF and reg dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity compared to other fluorescent dyes
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Biotium Secondary Antibody Dinitrophenyl DNP Rabbit CF750 1/EA
High-quality rabbit anti-dinitrophenyl (DNP) labeled with near-IR CF750 dye (Ex/Em 755/777 nm) CF dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity compared to other fluorescent dyes 2 mg/mL 50 uL
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Biotium Secondary Antibody Dinitrophenyl DNP Rabbit CF750 1/EA
High-quality rabbit anti-dinitrophenyl (DNP) labeled with far-red/near-IR CF750 dye (Ex/Em 755/777 nm) CF dyes are Biotiums line of next-generation fluorescent dyes with advantages in brightness photostability and conjugate specificity compared to other fluorescent dyes 2 mg/mL 250 uL
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Cayman Chemical CD45CTerm RabbIt Monclon 100uL
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A BET family protein inhibitor inhibits binding of BRD2 BRD3 and BRD4 to an acetylated histone H4 peptide in vitro decreases Myc levels in and inhibits proliferation of AML DLBCL and MM cells reduces tumor growth in AML DLBCL and MM mouse xenograft models reduces tumor growth when administered alone or in combination with docetaxel or MDV 3100 in a 22Rv1 CRPC mouse xenograft model
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Cayman Chemical Pax8CTerm RabbIt Monclon 100uL
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A flavone with diverse biological activities binds to rat adenosine A1 rat A2A and human A3 receptors (Kis 1 2 3 and 1 72 UM respectively in radioligand binding assays) inhibits DPP-4 (IC50 0 43 UM) active against the NF54 strain of P falciparum (IC50 16 9 UM) inhibits proliferation of AGS HT-29 Saos-2 and WEHI 164 cells (IC50s 14 4 13 1 38 5 and 40 7 UM respectively increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice at 10 mg/kg
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ABclonal Technology MAP3K4 Rabbit mAb
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This gene encodes MEKK4 (also known as MTK1) a MAPK kinase kinase (MAPKKK) that activates stress-responsive MAPK pathways MAPK cascades consist of three kinases a MAPKKK activates a MAPKK which then activates a MAPK MEKK4 specifically activates the CSBP2 (p38) and JNK pathways but not the ERK pathway It contains a kinase domain at the C-terminus and a potential regulatory domain at the N-terminus MEKK4 is activated by environmental stresses such as UV radiation osmotic shock and inflammatory signals In vitro MEKK4 phosphorylates and activates PRKMK6 and SERK1 MAPKKs for CSBP2 and JNK respectively but not PRKMK1 which activates ERKs MEKK4 is a key mediator of CSBP2 activation and a minor contributor to JNK signaling Multiple alternatively spliced isoforms of MEKK4 have been identified
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Cayman Chemical IgDhumn RabbIt Monclonal 100ug
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Immunogen: Human IgD • Host: Rabbit • Species Reactivity: (+) Human • Cross Reactivity: (+) IgD; (-) Human IgG, IgM, IgA, IgE • Applications: ELISA
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ABclonal Technology SARA Rabbit mAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway The encoded protein interacts directly with SMAD2 and SMAD3 and recruits SMAD2 to the TGFB receptor There are multiple pseudogenes for this gene on chromosomes 2 15 and X Alternative splicing results in multiple transcript variants
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American Research Products Inc Rabbit Krebs yon den Lundgen 6
Rabbit Krebs yon den Lundgen-6 (KL-6) ELISA Kit from CUSABIO Detection Range 50 IU/mL-800 IU/mL Sensitivity 25 IU/mL Sample serum plasma tissue homogenates Method Competitive
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Cayman Chemical InTRleukIn6 RabbIt MoncLN 50uL
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A p70S6K1 inhibitor (IC50 52 nM) selective for p70S6K1 over a panel of 43 kinases at 1 UM
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ABclonal Technology TCEB2 Rabbit mAb
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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This gene encodes the protein elongin B which is a subunit of the transcription factor B (SIII) complex The SIII complex is composed of elongins A A2 B and C It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units Elongin A functions as the transcriptionally active component of the SIII complex whereas elongins B and C are regulatory subunits Elongin A2 is specifically expressed in the testis and capable of forming a stable complex with elongins B and C The von Hippel-Lindau tumor suppressor protein binds to elongins B and C and thereby inhibits transcription elongation Two alternatively spliced transcript variants encoding different isoforms have been described for this gene Pseudogenes have been identified on chromosomes 11 and 13
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